Synthesis and pharmacological activity of 9-(4-bromophenyl)-7-phenyl-4,6-dihydro-1H-[1,4]diazepino[2,3-g]quinoxaline-2,3-dione is reported. The compounds are synthesized by the cyclization of 6,7-diaminoquinoxaline with different bromochalcones in the presence of alcohol. The structures are confined by IR, 1H NMR, mass and elemental analysis. The synthesized compounds were screened for analgesic, anti-inflammatory and ulcerogenic activities. The compounds had shown mild to good activity. The results had shown that the incorporation of diazepines to quinoxalines has produced good anti-inflammatory activity than analgesic activity.
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